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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P.K ; Pirastu, N ; Kentistou, K.A ; Fischer, K ; Hofer, E ; Schraut, K.E ; Clark, D.W ; Nutile, T ; Barnes, C.L.K ; Timmers, P ; Shen, X ; Gandin, I ; McDaid, A.F ; Hansen, T.F ; Gordon, S.D.S ; Giulianini, F ; Boutin, T.S ; Abdellaoui, A ; Zhao, W ; Medina-Gomez, C ; Bartz, T.M ; Trompet, S ; Lange, L.A ; Raffield, L ; Spek, A van der ; Galesloot, T.E ; Proitsi, P ; Yanek, L.R ; Bielak, L.F ; Payton, A ; Murgia, F ; Concas, M.P ; Biino, G ; Tajuddin, S.M ; Seppala, I ; Amin, N ; Boerwinkle, E ; Borglum, A.D ; Campbell, A ; Demerath, E.W ; Demuth, I ; Faul, J.D ; Ford, I ; Gialluisi, A ; Gogele, M ; Graff, M ; Hingorani, A ; Hottenga, J.J ; Hougaard, D.M ; Hurme, M.A ; Ikram, M.A ; Jylha, M ; Kuh, D ; Ligthart, L ; Lill, C.M ; Lindenberger, U ; Lumley, T ; Magi, R ; Marques-Vidal, P ; Medland, S.E ; Milani, L ; Nagy, R ; Ollier, W.E ; Peyser, P.A ; Pramstaller, P.P ; Ridker, P.M ; Rivadeneira, F ; Ruggiero, D ; Saba, Y ; Schmidt, R ; Schmidt, H ; Slagboom, P.E ; Smith, B.H ; Smith, J.A ; Sotoodehnia, N ; Steinhagen-Thiessen, E ; Rooij, F.J. van ; Verbeek, A.L ; Vermeulen, S.H ; Vollenweider, P ; Wang, Y ; Werge, T ; Whitfield, J.B ; Zonderman, A.B ; Lehtimaki, T ; Evans, M.K ; Pirastu, M ; Fuchsberger, C ; Bertram, L ; Pendleton, N ; Kardia, S.L ; Ciullo, M ; Becker, D.M ; Wong, A ; Psaty, B.M ; Duijn, C.M. van ; Wilson, J.G ; Jukema, J.W ; Kiemeney, L.A ; Uitterlinden, A.G

Nature communications, 2017, Vol.8 [Peer Reviewed Journal]

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2
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, Peter K ; Pirastu, Nicola ; Kentistou, Katherine A ; Fischer, Krista ; Hofer, Edith ; Schraut, Katharina E ; Clark, David W ; Nutile, Teresa ; Barnes, Catriona L. K ; Timmers, Paul R. H. J ; Shen, Xia ; Gandin, Ilaria ; McDaid, Aaron F ; Hansen, Thomas Folkmann ; Gordon, Scott D ; Giulianini, Franco ; Boutin, Thibaud S ; Abdellaoui, Abdel ; Zhao, Wei ; Medina-Gomez, Carolina ; Bartz, Traci M ; Trompet, Stella ; Lange, Leslie A ; Raffield, Laura ; van der Spek, Ashley ; Galesloot, Tessel E ; Proitsi, Petroula ; Yanek, Lisa R ; Bielak, Lawrence F ; Payton, Antony ; Murgia, Federico ; Concas, Maria Pina ; Biino, Ginevra ; Tajuddin, Salman M ; Seppälä, Ilkka ; Amin, Najaf ; Boerwinkle, Eric ; Børglum, Anders D ; Campbell, Archie ; Demerath, Ellen W ; Demuth, Ilja ; Faul, Jessica D ; Ford, Ian ; Gialluisi, Alessandro ; Gögele, Martin ; Graff, MariaElisa ; Hingorani, Aroon ; Hottenga, Jouke-Jan ; Hougaard, David M ; Hurme, Mikko A ; Ikram, M. Arfan ; Jylhä, Marja ; Kuh, Diana ; Ligthart, Lannie ; Lill, Christina M ; Lindenberger, Ulman ; Lumley, Thomas ; Mägi, Reedik ; Marques-Vidal, Pedro ; Medland, Sarah E ; Milani, Lili ; Nagy, Reka ; Ollier, William E. R ; Peyser, Patricia A ; Pramstaller, Peter P ; Ridker, Paul M ; Rivadeneira, Fernando ; Ruggiero, Daniela ; Saba, Yasaman ; Schmidt, Reinhold ; Schmidt, Helena ; Slagboom, P. Eline ; Smith, Blair H ; Smith, Jennifer A ; Sotoodehnia, Nona ; Steinhagen-Thiessen, Elisabeth ; van Rooij, Frank J. A ; Verbeek, André L ; Vermeulen, Sita H ; Vollenweider, Peter ; Wang, Yunpeng ; Werge, Thomas ; Whitfield, John B ; Zonderman, Alan B ; Lehtimäki, Terho ; Evans, Michele K ; Pirastu, Mario ; Fuchsberger, Christian ; Bertram, Lars ; Pendleton, Neil ; Kardia, Sharon L. R ; Ciullo, Marina ; Becker, Diane M ; Wong, Andrew ; Psaty, Bruce M ; van Duijn, Cornelia M ; Wilson, James G ; Jukema, J. Wouter ; Kiemeney, Lambertus ; Uitterlinden, André G ; ...

Nature communications, 2017-10-13, Vol.8 (1), p.910-910 [Peer Reviewed Journal]

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3
Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans
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Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

Krause-Kyora, Ben ; Nutsua, Marcel ; Boehme, Lisa ; Pierini, Federica ; Pedersen, Dorthe Dangvard ; Kornell, Sabin-Christin ; Drichel, Dmitriy ; Bonazzi, Marion ; Möbus, Lena ; Tarp, Peter ; Susat, Julian ; Bosse, Esther ; Willburger, Beatrix ; Schmidt, Alexander H ; Sauter, Jürgen ; Franke, Andre ; Wittig, Michael ; Caliebe, Amke ; Nothnagel, Michael ; Schreiber, Stefan ; Boldsen, Jesper L ; Lenz, Tobias L ; Nebel, Almut

Nature communications, 2018-05-01, Vol.9 (1), p.1569-1569 [Peer Reviewed Journal]

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4
A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis
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A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

Scally, Stephen W ; Petersen, Jan ; Law, Soi Cheng ; Dudek, Nadine L ; Nel, Hendrik J ; Loh, Khai Lee ; Wijeyewickrema, Lakshmi C ; Eckle, Sidonia B.G ; van Heemst, Jurgen ; Pike, Robert N ; McCluskey, James ; Toes, Rene E ; La Gruta, Nicole L ; Purcell, Anthony W ; Reid, Hugh H ; Thomas, Ranjeny ; Rossjohn, Jamie

The Journal of experimental medicine, 2013-11-18, Vol.210 (12), p.2569-2582 [Peer Reviewed Journal]

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5
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

Cleynen, Isabelle ; Boucher, Gabrielle ; Jostins, Luke ; Schumm, L Philip ; Zeissig, Sebastian ; Ahmad, Tariq ; Andersen, Vibeke ; Andrews, Jane M ; Annese, Vito ; Brand, Stephan ; Brant, Steven R ; Cho, Judy H ; Daly, Mark J ; Dubinsky, Marla ; Duerr, Richard H ; Ferguson, Lynnette R ; Franke, Andre ; Gearry, Richard B ; Goyette, Philippe ; Hakonarson, Hakon ; Halfvarson, Jonas ; Hov, Johannes R ; Huang, Hailang ; Kennedy, Nicholas A ; Kupcinskas, Limas ; Lawrance, Ian C ; Lee, James C ; Satsangi, Jack ; Schreiber, Stephan ; Théâtre, Emilie ; van der Meulen-de Jong, Andrea E ; Weersma, Rinse K ; Wilson, David C ; Parkes, Miles ; Vermeire, Severine ; Rioux, John D ; Mansfield, John ; Silverberg, Mark S ; Radford-Smith, Graham ; McGovern, Dermot P B ; Barrett, Jeffrey C ; Lees, Charlie W

The Lancet (British edition), 2016-01, Vol.387 (10014), p.156-167 [Peer Reviewed Journal]

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6
A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides
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A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides

Bossini Castillo, Lara ; Kovel, C. de ; Kallberg, H ; Slot, R. van 't ; Italiaander, A ; Coenen, M ; Tak, P. P ; Posthumus, M. D ; Wijmenga, Cisca ; Huizinga, Tom ; Helm-van Mil, A. H. M. van der ; Stoeken-Rijsbergen, G ; Rodríguez-Rodríguez, Luis ; Balsa, Alejandro ; González-Álvaro, Isidoro ; González-Gay, Miguel A ; Gómez Vaquero, Carmen ; Franke, B ; LifeLines Cohort Study ; Vermeulen, S ; Horst-Bruinsma, I. E. van der ; Dijkmans, B. A. C ; Wolbink, G. J ; Ophoff, R. A ; Maehlen, M. T ; Riel, P. van ; Merriman, M ; Klareskog, L ; Lie, Benedicte A ; Merriman, Tony ; Crusius, J. B. A ; Brouwer, E ; Martin, Javier ; Vries, N. de ; Toes, R ; Padyukov, Leonid ; Koeleman, Bobby P. C 2015

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7
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

Raychaudhuri, Soumya ; Sandor, Cynthia ; Stahl, Eli A ; Freudenberg, Jan ; Lee, Hye-Soon ; Jia, Xiaoming ; Alfredsson, Lars ; Padyukov, Leonid ; Klareskog, Lars ; Worthington, Jane ; Siminovitch, Katherine A ; Bae, Sang-Cheol ; Plenge, Robert M ; Gregersen, Peter K ; de Bakker, Paul I W

Nature genetics, 2012-01-29, Vol.44 (3), p.291-296 [Peer Reviewed Journal]

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8
Human leucocyte antigens and pediatric autoimmune liver disease: diagnosis and prognosis
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Human leucocyte antigens and pediatric autoimmune liver disease: diagnosis and prognosis

Junge, Norman ; Junge, Norman ; Tiedau, Miriam ; Tiedau, Miriam ; Verboom, Murielle ; Verboom, Murielle ; Hallensleben, Michael ; Hallensleben, Michael ; Blasczyk, Rainer ; Blasczyk, Rainer ; Schlue, Jerome ; Schlue, Jerome ; Goldschmidt, Imeke ; Goldschmidt, Imeke ; Pfister, Eva-Doreen ; Pfister, Eva-Doreen ; Baumann, Ulrich ; Baumann, Ulrich

European journal of pediatrics, 2016-04, Vol.175 (4), p.527-537 [Peer Reviewed Journal]

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9
Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk
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Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk

Hu, Xinli ; Deutsch, Aaron J ; Lenz, Tobias L ; Onengut-Gumuscu, Suna ; Han, Buhm ; Chen, Wei-Min ; Howson, Joanna M M ; Todd, John A ; de Bakker, Paul I W ; Rich, Stephen S ; Raychaudhuri, Soumya

Nature genetics, 2015-07-13, Vol.47 (8), p.898-905 [Peer Reviewed Journal]

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10
T Cell Epitope Mapping of JC Polyoma Virus-Encoded Proteome Reveals Reduced T Cell Responses in HLA-DRB104:01+ Donors
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T Cell Epitope Mapping of JC Polyoma Virus-Encoded Proteome Reveals Reduced T Cell Responses in HLA-DRB104:01+ Donors

Ilijas Jelčić ; Lilian Aly ; Thomas M. C. Binder ; Ivan Jelčić ; Sílvia Bofill-Mas ; Raquel Planas ; Victoria Demina ; Thomas H. Eiermann ; Thomas Weber ; Rosina Girones ; Mireia Sospedra ; Roland Martin

Journal of Virology, 2013-03-15, Vol.87 (6), p.3393-3408 [Peer Reviewed Journal]

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